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HPE ProLiant Gen12 rack and tower servers

A secure foundation to power new workloads while streamlining operations and cutting energy use. Gen12 spans Intel® Xeon® 6 rack and tower systems, NVIDIA accelerated platforms, and the NVIDIA® Vera CPU–based DL394 for agentic AI — all wrapped in the security, manageability, and lifecycle tooling enterprises trust from HPE ProLiant.

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HPE ProLiant Compute Gen12 server family
Up to 65%
Power savings per year vs. legacy systems
Up to 41%
Better performance per watt
iLO 7
FIPS 140-3 Level 3, quantum-resistant ready
7:1
One Gen12 server replaces seven Gen10 servers
Why Gen12

Next-generation ProLiant, engineered for what comes next

HPE ProLiant Compute Gen12 meets federal security certification standards, boosts IT productivity with AI-driven insights, and drives major power savings — right-sized for AI, data analytics, edge, hybrid cloud, and VDI.

Next-level security

HPE iLO 7 adds a dedicated secure-enclave security processor — the first server with quantum computing-resistant readiness and FIPS 140-3 Level 3 cryptographic certification.

Performance and efficiency

Up to 41% better performance per watt and up to 65% power savings per year, with optional direct liquid cooling on Intel-based one- and two-socket rack servers.

AI-driven productivity

HPE Compute Ops Management secures and automates server environments with AI-informed insights, map-based visibility, and third-party tool integration.

The Lineup

HPE ProLiant DL Gen12 servers

Rack-dense compute from 1U single-socket to 4U accelerated platforms, plus the Vera CPU–based DL394 built for agentic AI. Pick a model below or have us spec it for you.

DL394 Gen12

2U server powered by the NVIDIA® Vera CPU — built for agentic AI and reinforcement learning, with 88 Olympus cores and up to 1.2 TB/s memory bandwidth. Explore the DL394

DL320 Gen12

1U single-socket rackmount that maximizes rack utilization while mitigating virtualization risks in power-constrained environments. View models

DL340 Gen12

2U single-socket server with reduced power draw and better thermals for data- and storage-centric workloads that need more PCIe lanes. View models

DL360 Gen12

Compact 1U 2P server delivering exceptional compute performance, memory density, scalability, and high-speed data transfer for demanding applications. View models

DL380 Gen12

Two-socket scalable server that powers data analytics and supports hybrid cloud workloads. View models

DL380a Gen12

4U accelerated platform with 6th Gen Intel® Xeon® (64–144 core), up to 4 TB RDIMM, SFF NVMe and EDSFF storage, and up to 8 M-CRPS power supplies. Contact us to configure

DL384 Gen12

NVIDIA Grace CPU and Hopper GPU platform with up to 8 EDSFF NVMe Gen5 drives and up to 4 HPE 1800W–2200W Flex Slot Titanium power supplies. Contact us to configure

The Lineup

HPE ProLiant ML Gen12 servers

Tower form factors for offices and edge sites that need datacenter-class capability without a datacenter.

ML350 Gen12

Robust 2P tower server with an optional rackable chassis, delivering exceptional compute performance, security, reliability, and expandability for varied environments. View models

What's Inside Gen12

Security, efficiency, and AI operations as standard

Every Gen12 server inherits the same foundation, so the choice between models is about form factor and workload — not about giving up protection or manageability.

  • HPE iLO 7 secure enclaveDedicated HPE-designed security processor, quantum-resistant readiness, and FIPS 140-3 Level 3 certification.
  • Up to 41% better performance per wattRight-sized for AI, data analytics, edge, hybrid cloud, and VDI, with optional direct liquid cooling.
  • Up to 65% annual power savingsOne Gen12 server delivers the compute of seven Gen10 servers, freeing data center capacity.
  • HPE Compute Ops ManagementCloud-based, AI-informed insights, map-based visibility, and third-party tool integration for Gen10 and newer.
HPE ProLiant Compute Gen12 server family
Authorized HPE Partner

Eight Gen12 models, one right answer for your workload

Processor family, memory, storage, networking, GreenLake consumption, and lead times differ across the DL and ML lineup. Tell us what your workloads need to do, and we'll land you on the right Gen12 build, get you pricing that makes sense, and stay on the order until it's racked.

  • Configuration guidance from people who know the HPE ProLiant catalog
  • Authorized-partner pricing, without the usual procurement friction
  • Order follow-through — from quote to delivery
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Availability

When the Gen12 portfolio ships

Q1 2025

Six of the eight new Intel Xeon 6–based Gen12 servers ship first: DL320, DL340, DL360, DL380, DL380a, and ML350 Gen12.

Summer 2025

HPE Synergy 480 and HPE ProLiant Compute DL580 Gen12 servers are expected to follow.

Standalone or GreenLake

The full Gen12 portfolio is available as a standalone purchase or as a service via HPE GreenLake.

Resources

Datasheets & downloads

HPE ProLiant Compute Gen12 Servers
Portfolio overview: security, efficiency, and AI operations (PDF)
DL394 Gen12 Solution Brief
CPU-optimized powerhouse for the era of agentic AI (PDF)
Get Started

Build your Gen12 server today

Tell us about your workloads and a ServerComputeWorks specialist will help you choose, configure, price, and order the right HPE ProLiant Gen12 system.

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*Intel and Xeon are trademarks of Intel Corporation. NVIDIA, Vera, Grace, and Hopper are trademarks and/or registered trademarks of NVIDIA Corporation. SPEC and SPECrate are registered trademarks of the Standard Performance Evaluation Corporation. FIPS 140-3 Level 3 certification is a standard adopted by NIST and CNSA 2.0. Performance and power-savings claims are based on internal HPE measurements and SPECrate2017_int_base results published on spec.org. All other third-party trademark(s) is/are property of their respective owner(s). Specifications and availability are subject to change.