HPE ProLiant DL380 Gen11 4510 Server
12‑core 64GB‑R

Overview:

Are you looking for a dual-socket scalable server solution to power data analytics or hybrid cloud workloads?

The HPE ProLiant DL380 Gen11 server is a scalable 2U 2P solution that delivers exceptional compute performance, memory density with scalability and high-speed data transfer rate to run your most demanding applications

Powered by 4th and 5th Gen Intel® Xeon® Scalable Processors with up to 64 cores, 8 TB of memory, and 20 EDSFF drive as well as increased memory bandwidth and high-speed PCIe Gen5 I/O, the HPE ProLiant DL380 Gen11 server is a perfect solution for software-defined storage, video transcoding, and virtualized apps.

The HPE ProLiant DL380 Gen11 server is engineered to optimize IT with a cloud operating experience, built-in security, and optimized performance for workloads to drive your business forward.

What's New

• Powered by the 4th and 5th Gen Intel® Xeon® Scalable Processors with next-generation technology that support up to 64 cores at 350W and 16 DIMMs for DDR5 memory at speeds up to 5600 MHz.
• Support for up to 8 TB total DDR5 memory with 16 DIMM channels per processor delivers increased performance, lower power requirements, and High Bandwidth Memory (HBM) support.
• Support for PCIe Gen5, resulting in improved bandwidth, advanced data transfer rates, and higher network speeds from the PCIe Gen5 serial expansion bus.
• Includes the new HPE Integrated Lights-Out 6 (iLO 6) server management software that enables you to securely configure, monitor, and update your HPE ProLiant Gen11 servers seamlessly, from anywhere.
• Supports hot-pluggable, high-availability RAID M.2 boot options.
• Supports up to 8 single wide (SW) or 3 double wide (DW) GPUs to accelerate graphic intense workloads.

Features:

Intuitive Cloud Operating Experience: Simple, Self-service, and Automated

HPE ProLiant DL380 Gen11 servers are engineered for your hybrid world. HPE ProLiant DL380 Gen11 servers simplify the way you control your business’s compute—from edge to cloud—with a cloud operating experience.

Transform business operations and pivot your team from reactive to proactive with global visibility and insight through a self-service console.

Automate tasks for efficiency in deployment, instant scalability, and seamless, simplified support and lifecycle management reducing tasks and shortening maintenance windows.

These experiences are engineered and built into all HPE ProLiant Gen11 servers, whether purchased as physical servers or consume as-a-service using HPE GreenLake as your compute and storage demands grow.

Simplify and secure server management from edge to cloud with HPE GreenLake for Compute Ops Management. HPE GreenLake for Compute Ops Management is an as-a-service compute management experience that delivers greater simplicity, agility, and speed across your entire compute landscape, globally.

Trusted Security by Design: Uncompromising, Fundamental, and Protected

The HPE ProLiant DL380 Gen11 server utilizes the HPE Silicon Root of Trust, HPE’s fundamental approach to security that provides zero-trust architecture at the silicon level and ensures all server essential firmware is free from malware or compromised code.

The server, powered by 4th and 5th Gen Intel® Xeon® Scalable Processors, adds hardware and software-assisted security features, including Intel® Software Guard Extensions and Intel® Boot Guard, which secure the server hardware foundation on which critical apps run and better protect data in memory.

HPE ProLiant Gen11 servers continuously protect healthy servers by providing rapid detection of security-compromised servers, even to the point of not allowing them to boot if it identifies and contains malicious code, and secure servers at the edge with IDevID certificates installed by default.

HPE ProLiant servers provide automated recovery from a security event, including restoration of validated firmware, and facilitating recovery of operating system, application and data connections, providing the fastest path to bring a server back online and into normal operations.

From silicon to software, from factory to cloud, and from generation to generation, HPE ProLiant Gen11 is engineered with a fundamental security approach to defend against increasingly complex threats through an uncompromising commitment to constant security advancements that are built into our DNA.

Optimized Performance for your Workloads: Accelerated, Open, and Efficient

The HPE ProLiant DL380 Gen11 server is an excellent choice for compute and data storage demanding workloads (AI, ML, telco, DB analytics, VDI, containers) requiring maximum core count, GPU capabilities, and network and I/O bandwidth.

Harness major computer performance. The HPE ProLiant DL380 Gen11 server is powered by 4th and 5th Gen Intel® Xeon® Scalable Processors with next-generation technology that supports up to 64 cores per processor, 350W, and up to 8 TB of memory.

The HPE ProLiant DL380 Gen11 server provides advanced data transfer rates and higher network speeds from the PCIe Gen5 serial expansion bus, with up to 2 x16 PCIe Gen5 and 2 OCP slots to improve I/O throughput and reduce latency.

It provides 16 DIMM channels per processor for up to 8 TB total DDR5 memory with increased memory bandwidth and performance, and lower power requirements.

It provides real-time operational feedback on server performance plus recommendations for fine-tuning BIOS settings to customize for changing business needs.

Available in an As-a-Service Experience

The HPE ProLiant DL380 Gen11 server is supported by HPE GreenLake to simplify IT infrastructure management across your entire hybrid estate. With 24x7 monitoring and management, our experts do the heavy lifting to manage your environment with services built into consumption-based solutions.

Hewlett Packard Enterprise provides customers with choices in how they acquire and consume IT beyond traditional financing and leasing, offering options that free trapped capital, accelerate infrastructure updates, and provide on-premises pay-per-use consumption with HPE GreenLake.

Technical Specifications:

HPE ProLiant DL380 Gen11 4510 2.4GHz 12c 1P 64GB‑R 12LFF MR416i‑o 2x8TB HDD 2x1000W PS NA Server Specifications
Detailed product description	HPE ProLiant DL380 Gen11 12 LFF server with one Intel® Xeon® Silver 4510 processor, 64 GB DDR5 RDIMM memory, Broadcom MR416i-o storage controller, two 8 TB SATA HDDs, and two HPE 1000W Flex Slot Titanium Hot Plug Power Supply Kits
Product Number	P72981-005
Processor name	Intel® Xeon® Silver 4510 (12 core, 2.40 GHz, 30 MB L3, 150W)
Processor number	1 processor included
Processor core available	12 core
Processor cache	30 MB L3
Processor speed	2.40 GHz
Power supply type	2x HPE 1000W Flex Slot Titanium Hot Plug Power Supply Kit
Expansion slots	Up to 8 PCIe Gen5, and 2 OCP 3.0, for detailed descriptions reference the QuickSpecs
Memory type	HPE DDR5 Smart Memory
Included hard drives	2x 8TB SATA HDD
Optical drive type	Optional DVD-ROM Optional via Universal Media Bay External support only
System fan features	4x Standard Fans
Network controller	Broadcom BCM5719 Ethernet 1Gb 4-port BASE-T OCP3 Adapter for HPE
Storage controller	HPE MR416i-o Gen11 x16 Lanes 8GB Cache OCP SPDM Storage Controller
Infrastructure management	HPE iLO Standard with intelligent provisioning (embedded), HPE OneView Standard (requires download) (standard) HPE iLO Advanced, HPE OneView Advanced (optional, requires licenses), and HPE GreenLake COM
Warranty	Server Warranty includes three years of parts, three years of labor, and three years of onsite support coverage

Hardware Specs:

Services & Add-Ons:

• HPE Tech Care
• HPE iLO Advanced
• Windows Server 2025
• Storage Options
• Memory (RAM Options)
• Quick Recommendations

Documentation:

Download the HPE ProLiant DL380 Gen11 4510 2.4GHz 12c 1P 64GB‑R 12LFF MR416i‑o 2x8TB HDD 2x1000W PS NA Server Data sheet (.PDF)

Download the HPE ProLiant DL380 Gen11 server Datasheet (.PDF)

Download the HPE ProLiant DL380 Gen11 server Quick Specs (.PDF)