Overview:
Are you looking for a single-socket scalable server solution to power your virtualized data-intense, large-capacity storage workloads?
The HPE ProLiant DL345 Gen11 server is a scalable 2U 1P solution that delivers exceptional compute performance and large capacity storage options at 1P economics. Powered by 4th Generation AMD EPYC™ Processors with up to 96 cores, increased memory bandwidth (up to 3 TB1), high-speed PCIe Gen5 I/O and EDSFF2 storage, up to 20 LFF/ 34 SFF, and up to four GPUs at the front2, this server is a superb single-socket 2U solution for your data-intensive workloads. Enhanced security features with the silicon root of trust from HPE are built into the firmware, creating a digital fingerprint for the AMD Secure Processor to validate safe operation prior to boot. The HPE ProLiant DL345 Gen11 server provides impressive storage performance and options for data-intensive workloads such as software-defined storage, video transcoding, and virtualized apps.
What's New
- Powered by the 4th Generation AMD EPYC™ Processors with 5nm technology that supports up to 96 cores at 400 W, 384 MB of L3 cache, and 12 DIMMs for DDR5 memory up to 4800MT/s.
- 12 DIMM channels per processor for up to 3 TB1 total DDR5 memory with increased memory bandwidth and performance, and lower power requirements.
- Advanced data transfer rates and higher network speeds from the PCIe Gen5 serial expansion bus, with up to 6x16 PCIe Gen5 and two OCP slots.
- Includes HPE Integrated Lights-Out 6 (iLO 6) server management software that enables you to securely configure, monitor, and update your HPE ProLiant Gen11 servers seamlessly from anywhere.
- Supports hot-pluggable, high-availability RAID M.2 boot options.
- Supports mid/rear drive bay options, total of up to 34 SFF / 20 LFF drives
Note:
1 Maximum memory capacity support available Q1 2023. Subject to change.
2 Enterprise and Data Center SSD Form Factor (EDSFF) and GPUs chassis support available Q1 2023. Subject to change.
Features:
Intuitive Cloud Operating Experience: Simple, Self-service, and Automated
HPE ProLiant DL345 Gen11 servers are engineered for your hybrid world. The HPE ProLiant Gen11 servers simplify the way you control your business’s compute—from edge to cloud—with a cloud operating experience.
Transform business operations and pivot your team from reactive to proactive with global visibility and insight through a self-service console.
Automate tasks for efficiency in deployment and instant scalability for seamless, simplified support and lifecycle management, reducing tasks and shortening maintenance windows.
These experiences are engineered and built into all HPE ProLiant Gen11 servers, whether purchased as physical servers or consumed as-a-service using HPE GreenLake as your compute and storage demands grow.
Simplify and secure server management from edge to cloud with HPE GreenLake for Compute Ops Management HPE GreenLake for Compute Ops Management is an as-a-service compute management experience that delivers greater simplicity, agility, and speed across your entire compute landscape, globally.
Trusted Security by Design: Uncompromising, Fundamental, and Protected
The HPE ProLiant DL345 Gen11 server is tied into the silicon root of trust and the AMD Secure Processor, a dedicated security processor embedded in the AMD EPYC™ system on a chip (SoC), to manage secure boot, memory encryption, and secure virtualization.
HPE ProLiant Gen11 servers use the silicon root of trust to anchor the firmware of an HPE ASIC, creating an immutable fingerprint for the AMD Secure Processor that must be matched exactly before the server will boot. This helps ensure malicious code is contained, and healthy servers are protected.
HPE ProLiant Gen11 servers continuously protect healthy servers at the edge by providing rapid detection of security-compromised servers, even to the point of not allowing them to boot if it identifies and contains malicious code, with IDevID certificates installed by default.
HPE ProLiant Gen 11 servers provide automated recovery from a security event, including restoration of validated firmware, and facilitating recovery of the operating system, application, and data connections, and providing a fast path to bring a server back online and into normal operations.
From silicon to software, from factory to cloud, and from generation to generation, HPE ProLiant Gen11 is engineered with a fundamental security approach to defend against increasingly complex threats through an uncompromising commitment to constant security advancements that are built into our DNA.
Customized Performance for your Workloads: Accelerated, Open, and Efficient
The HPE ProLiant DL345 Gen11 server is an excellent choice for data-intensive workloads such as software-defined storage, video transcoding, and such, and virtualized apps that require large storage capacity, and high I/O and memory bandwidth.
Harness major computer performance. The HPE ProLiant DL345 Gen11 server is powered by the 4th Generation AMD EPYC™ Processors with 5nm technology that supports up to 96 cores, 400W, and 384 MB of L3 cache.
Advanced data transfer rates and higher network speeds from the PCIe Gen5 serial expansion bus, with up to 2x16 PCIe Gen5 and 2 OCP slots, improve I/O throughput and reduce latency.
Increase memory bandwidth and performance, and lower power requirements with 12 DIMM channels per processor for up to 3 TB1 total DDR5 memory.
Provide real-time operational feedback on server performance plus recommendations for fine-tuning BIOS settings to customize for changing business needs.
Hardware Specs:
HPE ProLiant DL345 Gen11 server

Front View - 24 SFF chassis shown
1 |
Quick removal access panel |
2 |
Health LED |
3 |
Power On/Standby button and system power LED |
4 |
iLO service port |
5 |
NIC status LED |
6 |
USB 3.2 Gen1 Port |
7 |
Unit ID button/ LED |
8 |
Box 3 - 8 SFF Drive Cage Bay |
9 |
Box 2 - 8 SFF Drive Cage Bay |
10 |
Box 1 - 8 SFF Drive Cage Bay |
11 |
Serial number pull tab1 |
Notes:
- Maximum Memory Capacity, EDSFF and GPU Mode-X support available 1H 2023, subject to change
- 1Optional: Universal Media Bay

Internal View – 2 SFF rear cage shown
1 |
Megacell battery holder |
2 |
Hard drive backplane power connectors |
3 |
Chassis intrusion detection connector |
4 |
Up to 2 Hot Plug redundant HPE Flexible Slot Power supplies (Under) |
5 |
Rear 2 SFF Cage Bay (Optional) |
6 |
Secondary PCIe 5.0 risers, slot 4,5,6 |
7 |
OCP 3.0 Slot 22 (Under) |
8 |
Internal Dual USB 3.2 Gen1 port |
9 |
Primary PCIe 5.0 risers, slot 1,2,3 |
10 |
OCP 3.0 Slot 21 (Under) |
11 |
DDR5 DIMM slots1 |
12 |
FHFL PCIe card holder |
13 |
Up to 1 Processor shown with standard heat sink2 |
14 |
Hot plug fans3,4 |
Notes:
- 1 Fully populated 12 DIMMs shown
- 2 Optional: Performance Heat Sink
- 3 6 single rotor standard shown
- 4 Optional: Performance Fans

Rear View - 2 SFF rear cage shown
1 |
Primary PCIe 5.0 Riser1 |
2 |
Secondary PCIe 5.0 Riser2 |
3 |
Optional Rear Drive Cage (2SFF SAS/SATA/NVMe) |
4 |
Optional NS204i-u hot-plug NVMe boot device> |
5 |
Hot-plug Power Supply 1 |
6 |
Hot-plug Power Supply 2 (Optional) |
7 |
Video (VGA) port |
8 |
OCP 3.0 slot 22 |
9 |
Optional Serial port |
10 |
Dedicated iLO management port |
11 |
2 USB 3.2 Gen1 port |
12 |
Unit ID LED |
11 |
OCP 3.0 slot 21 |
Notes:
- 1 PCIe Slots 1,2,3 top to bottom.
- 2 PCIe Slots 4,5,6 top to bottom.
Services:
HPE POINTNEXT SERVICES
HPE Pointnext Services brings together technology and expertise to help you drive your business forward and prepare for whatever is next.
Operational Services from HPE Pointnext Services
HPE Pointnext Tech Care provides fast access to product-specific experts, an AI-driven digital experience, and general technical guidance to help enable constant innovation. We have reimagined IT support from the ground up to deliver faster answers and greater value. By continuously searching for better ways to do things—as opposed to just fixing things that break—HPE Pointnext Tech Care helps you focus on achieving your business goals.
HPE Pointnext Complete Care is a modular, edge-to-cloud IT environment service that provides a holistic approach to optimizing your entire IT environment, and achieving agreed upon IT outcomes and business goals through a personalized and customer-centric experience. All delivered by an assigned team of HPE Pointnext Services experts.
HPE Integration and Performance Services help you customize your experience at any stage of your product lifecycle with a menu of services based on individual needs, workloads, and technologies.
- Advise, design, and transform
- Deploy
- Integrate and migrate
- Operate and improve
- Financial Services
- Greenlake Management Services
- Retire and sanitize
- IT Training and personal development
Other related services
HPE Education Services delivers a comprehensive range of services to support your people as they expand their skills required for a digital transformation. Consult your HPE Sales Representative or Authorized Channel Partner of choice for any additional questions and support options.
Defective Media Retention is optional and allows you to retain Disk or eligible SSD/Flash Drives replaced by HPE due to malfunction.
HPE GREENLAKE
HPE Greenlake is HPE’s market-leading IT as-a-Service offering that brings the cloud experience to apps and data everywhere – data centers, multi-clouds, and edges – with one unified operating model. HPE GreenLake delivers public cloud services and infrastructure for workloads on premises, fully managed in a pay per use model.